Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage

Table 23

Analysis of the combined effects of IL-10 and TLR4 SNPs on the risk of miscarriage with multiple logistic regression.

	Estimate	Std. error	z value	Pr (>|z|)
(Intercept)	−4.756e + 13	7.255e + 13	−0.656	0.512
IL-10 CC + TLR4 CC	4.756e + 13	7.255e + 13	0.656	0.512
IL-10 AA + TLR4 CC	4.551e + 15	7.255e + 13	62.728	<2e − 16
IL-10 CA + TLR4 CC	4.756e + 13	7.255e + 13	0.656	0.512
IL-10 CC + TLR4 CT	4.756e + 13	7.255e + 13	0.656	0.512
IL-10 CA + TLR4 CT	4.551e + 15	7.255e + 13	62.728	<2e − 16

Significance codes: 0 ‘’ 0.001 ‘’ 0.01 ‘’ 0.05 ‘.’ 0.1 ‘ ’ 1.