Research Article

Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage

Table 26

Major triple genetic interactions that affect the risk of miscarriage.

Increasing risk of miscarriageDecreasing risk of miscarriage

TLR9 GA + IL-10 AA + TLR4 CCTLR9 GG + IL-10 CC + TLR4 CC
TLR9 GA + IL-10 AA + TLR4 CTTLR9 GG + IL-10 CA + TLR4 CC
TLR9 AA + IL-10 CA + TLR4 CT
TLR9 AA + IL-10 CA + TLR4 CC