Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage

Table 6

TLR9 G2848A polymorphism analysis with general additive model of inheritance.

Genotype	Women with miscarriage frequency	Control group frequency	χ^2		Odds ratio
					Values	95% CI
GG	0.283	0.757	43.40	4.0E-10	0.13	0.06–0.25
GA	0.358	0.203			2.20	1.10–4.39
AA	0.358	0.041			13.23	3.90–44.87

Estimated genotype frequencies as well as corresponding odds ratios and 95% confidence interval (significance level of 0.05) in the group of women with miscarriage and the control group.