Research Article

Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome

Table 1

Comparison between control and PCOS women.

ParametersControlPCOS value

Number4443
Age (years), mean ± SD0.162
Parity, median (IQR)1 (0.25–2.0)2 (1–3)0.120
Kisspeptin (ng/L), median (IQR)235.3 (220.6–258.4)322.4 (254.6–377.1)<0.001
BMI, n (%)
 <25 kg/m221 (47.7%)23 (53.5%)0.591
 ≥25 kg/m223 (52.3%)20 (46.5%)
Hirsutism, n (%)0 (0%)43 (100%)<0.001
Acne, n (%)18 (40.9%)27 (62.8%)0.041
Elevated LH, n (%)14 (31.8%)27 (62.8%)0.004
FSH, n (%)
 Normal31 (70.5%)28 (65.1%)0.700
 Decreased9 (20.5%)12 (27.9%)
 Elevated4 (9.1%)3 (7%)
 Increased TSH, n (%)11 (25%)13 (30.2%)0.585
 Increased PRL, n (%)20 (45.5%)15 (34.9%)0.315
SHBG, n (%)
 Normal31 (70.5%)29 (67.4%)0.952
 Decreased11 (25%)12 (27.9%)
 Elevated2 (4.5%)2 (4.7%)
 Increased testosterone, n (%)18 (40.9%)28 (65.1%)0.024
DHEAS, n (%)
 Normal31 (70.5%)30 (69.8%)0.923
 Decreased8 (18.2%)7 (16.3%)
 Elevated5 (11.4%)6 (14%)
Glycemic status, n (%)
 Normal25 (56.8%)21 (48.8%)0.695
 Decreased9 (20.5%)9 (20.9%)
 Elevated10 (22.7%)13 (30.2%)
 Impaired lipid profile14 (31.8%)16 (37.2%)0.597

SD: standard deviation, n: number, IQR: interquartile range (25th–57th percentile), PRL: prolactin, SHBG: sex hormone-binding globulin, T: testosterone, DHEAS: dehydroepiandrosterone sulfate, and FPG: fasting blood glucose.