Does Luteal Phase Support Effect Pregnancy Rates in Intrauterine Insemination Cycles? A Prospective Randomised Controlled Study in a Tertiary Center

Table 1

Patient demographic characteristics and cycle characteristics.

	Control group (n = 43)	Study group (n = 44)	value
Age
Median (min-max)	27 (21–34)	28 (22–33)	0.27
Mean ± SD	26.7 ± 3.9	28 ± 4.1
BMI (kg/m^2)
Median (min-max)	23.2(18–25)	22.1(10–24.6)	0.78
Mean ± SD	22.1 ± 2.8	21.6 ± 2.8
Duration of infertility (yrs) (mean ± SD)	2.8 ± 3	2.6 ± 3.5	0.27
Cause of infertility
Unexplained	42 (97.6%)	42 (95.4%)	0.074
Male subfertility	1 (2.3%)	2 (4.7%)
Basal sperm count (×10^6)
Mean±SD	105.5 ± 58.2	89.3 ± 61.3	0.042
Median (min-max)	105 (11–320)	83 (12–250)
Sperm count after washing (mean ± SD)	56.7 ± 31.3	55 ± 29.2	0.41
Sperm motility after washing (%)	51.3% ± 14.7	50.2% ± 15.3	0.47
Basal FSH (mIU/mL)
Mean	5.9	6.1	0.25
Median (min-max)	7 (3−10.2)	7.1 (3.5–10.1)
Basal E2 (pg/mL)
Mean	46.3	47.2	0.77
Median (min-max)	35 (20–60)	37 (10–60)
Basal progesterone (ng/mL) (mean ± SD)	2.3 ± 3.1	2.5 ± 2.9	0.90
Basal LH (mIU/mL) (mean ± SD)	7.2 ± 2.8	5.6 ± 3.4	0.52
Basal PRL (ng/mL) (mean ± SD)	12 ± 3.4	14.1 ± 7.6	0.43
Basal TSH (µIU/mL) (mean ± SD)	1.9 ± 1.2	2,7 ± 1,6	0.35
Antral follicle count
Mean±SD	6.9 ± 2.1	7.1 ± 3.4	0.31
Median (min-max)	8 (4−12)	9 (4–13)
Endometrial thickness on the day of hCG (mm) (mean ± SD)	11.2 ± 1.6	10.9 ± 1.4	0.92
Number of follicles with a diameter of 9–16 mm on the day of hCG
Mean±SD	3 ± 1.6	2.5 ± 1.5	0.54
Median (min-max)	3 (0–5)	4 (0–6)
Number of follicles with a diameter ≥17 mm on the day of hCG
Mean±SD	1.1 ± 0.5	1.4 ± 0.6	0.34
Median (min-max)	2 (1–2)	2 (1–2)
Gonadotropin type
Menotrophin	2 (4.6%)	4 (9.09%)	0.81
hpHMG	14 (32.5%)	1 (2.27%)	0.03
Follitropin α	9 (20.9%)	10 (22.7%)	0.90
Follitropin β	18 (41.8%)	29 (65.9%)	0.08
Duration of stimulation (days) (mean ± SD)	6.7 ± 3.4	7.2 ± 2.4	0.72
Total amount of gonadotropin (IU)	850 ± 510	890 ± 610	0.43