Prevalence of Hepatitis B Carrier Status and Its Negative Association with Hypertensive Disorders in Pregnancy

Table 3

Incidence of hypertensive complications in pregnancy.

	Total (n = 87889)			2000–2004 (n = 19523)			2005–2009 (n = 24261)			2010–2014 (n = 24343)			2015–2019 (n = 19763)
	HBV −ve (n = 79487)	HBV +ve (n = 8402) (9.56%)	value	HBV −ve (n = 17527)	HBV +ve (n = 1996) (10.2%)	value	HBV −ve (n = 21583)	HBV +ve (n = 2678) (11.05%)	value	HBV −ve (n = 21966)	HBV +ve (n = 2377) (9.7%)	value	HBV −ve (n = 18411)	HBV +ve (n = 1351) (6.8%)	value
Gestational hypertension^a	2366 (2.97%)	185 (2.20%)	<0.001	524 (2.98%)	34 (1.70%)	<0.01	607 (2.81%)	57 (2.12%)	0.041	683 (3.11%)	63 (2.65%)	0.21	552 (2.99%)	31 (2.29%)	0.14
PET without chronic HT^b	1103 (1.25%)	66 (0.78%)	<0.001	195 (1.11%)	12 (0.60%)	0.047	282 (1.30%)	19 (0.71%)	0.043	319 (1.45%)	23 (0.97%)	0.07	307 (1.67%)	12 (0.89%)	0.038
Chronic HT	168 (0.21%)	19 (0.22%)	0.87	13 (0.07%)	1 (0.05%)	0.94	34 (0.15%)	4 (0.15%)	0.87	54 (0.24%)	6 (0.25%)	0.85	67 (0.36%)	8 (0.59%)	0.27
PET superimposed on chronic HT^c	60 (0.07%)	4 (0.04%)	0.24	9 (0.05%)	0	—	17 (0.08%)	3 (0.11%)	0.76	14 (0.06%)	0	—	20 (0.11%)	1 (0.07%)	0.95
Eclampsia^d	37 (0.04%)	5 (0.06%)	0.68	12 (0.07%)	2 (0.1%)	0.94	12 (0.06%)	3 (0.11%)	0.95	8 (0.03%)	0	—	5 (0.03%)	0	—
All PET^(e=b+c+d)	1200 (1.50%)	75 (0.89%)	<0.001	216 (1.23%)	14 (0.70%)	0.037	311 (1.44%)	25 (0.93%)	0.034	341 (1.55%)	23 (0.97%)	0.016	332 (1.80%)	13 (0.96%)	0.023
Total hypertensive disorders^(a+e)	3566 (4.48%)	260 (3.09%)	<0.001	740 (4.22%)	48 (2.40%)	<0.001	918 (4.25%)	82 (3.06%)	0.001	1024 (4.66%)	86 (3.62%)	0.02	884 (4.80%)	44 (3.26%)	0.01

PET = preeclampsia, HT = hypertension.