Research Article

Prevalence of Hepatitis B Carrier Status and Its Negative Association with Hypertensive Disorders in Pregnancy

Table 4

Major risk factors for women with or without preeclampsia and all pregnancy hypertensive disorders.

PET (n = 1275) (1.45%)No PET (n = 86614) (98.55%) valueAll gestational hypertensive disorders (n = 3826) (%)No gestational hypertension (n = 84063) (%) value

Chinese ethnicity1263 (99%)85429 (98.6%)0.1923784 (98.9%)82895 (98.6%)0.11
Parity
 Nulliparous691 (54.2%)42569 (49.1)<0.0012071 (54.1%)41189 (49%)<0.001
 Multiparous584 (45.8%)44045 (50.9%)1755 (45.9%)42875 (51%)

Advanced maternal age (>35)414 (32.5%)23499 (27.1%)<0.0011169 (30.6%)22744 (27.1%)<0.001
Multiple pregnancies46 (3.6%)1437 (1.65%)<0.001126 (3.29%)1357 (1.61%)<0.001
Obesity (body mass index >25 kg/m2)360 (28.2%)19962 (23%)<0.001950 (24.8%)19372 (23%)0.01
Smoking21 (1.64%)1736 (2%)0.3671 (1.85%)1686 (2.01%)0.52
Medical disorders45 (3.53%)942 (1.08%)<0.00176 (1.98%)911 (1.08%)0.001
Hepatitis B carrier status75 (5.88%)8327 (9.61%)<0.001260 (6.79%)8142 (9.68%)<0.001

All significant medical disorders that could predispose to gestational hypertension/preeclampsia, such as chronic hypertension, renal disorders, preexisting and gestational diabetes mellitus, and autoimmune disorders.