Research Article

Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon

Table 2

Cervical cytology screening in women who were not initially sexually active and received the human papilloma virus vaccine at the Women’s Health Center (WHC) of the American University of Beirut-Medical Center (AUBMC) 2007–2017.

Bivalent vaccineQuadrivalent vaccineTotal value

Age at vaccination (years)Mean ± SD25.9 ± 4.928 ± 4.727.7 ± 4.70.003
Median (range)25 (17–38)27 (18–45)27 (17–45)
N (%)48 (18%)219 (82%)267
% Of ladies >25 years old at first dose of vaccination47.9%70.3%66.3%0.003
(23/48)(154/219)(177/267)
Age at first pap smear after vaccination (years)Mean27.7 ± 3.929.2 ± 5.029.0 ± 4.90.057
Median (range)28 (18–38)28 (19–46)28 (18–46)
N48219267
% Of ladies >25 years old at first Pap smear70.8%79%77.5%0.25
(34/48)(173/219)(207/267)
Incidence of abnormal Pap smear postvaccinationN (%)(4/48) 8%(10/267) 4.6%(14/267) 5%0.022
Age at abnormal pap smear postvaccine (years)Mean31.3 ± 3.932 ± 4.032 ± 3.90.637
Median (range)32 (26–35)32 (26–40)32 (26–40)
% Of females >25 years old at time of vaccination with subsequent abnormal Pap smear50% (2/4)60% (6/10)57.1% (8/14)0.733

Subsequent Pap smear results following HPV vaccination
Normal25391.7% (44/48)95.4% (209/219)94.8% (253/267)0.022
ASCUS104.2% (2/48)3.7% (8/219)3.7% (10/267)
LSIL20%-(0/48)1.0% (2/219)0.75% (2/267)
HSIL/CIS24.2% (2/48)0.0% (0/219)0.75% (2/267)