Obstetrics and Gynecology International

Human Pregnancy and Parturition Clinical Management

Publishing date
01 Jun 2010
Submission deadline
01 Dec 2009

1Department of Obstetrics and Gynecology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain

2Department of Obstetrics, Gynecology & Reproductive Sciences, Health Science Center at Houston, The University of Texas, Houston, TX 77030, USA

3Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06519, USA

4Department of Obstetrics and Gynaecology, Flinders University, Flinders Medical Centre, Adelaide, Australia

5Department of Obstetrics and Gynecology, Juan M. Fernández Hospital, Buenos Aires University, Buenos Aires, Argentina

6Department of Biomedical Sciences, Mercer University School of Medicine, 4700 Waters Avenue, Savannah, GA 31405, USA

Human Pregnancy and Parturition Clinical Management


Spontaneous onset of labor and delivery at term should be the goals for pregnancy whenever possible. Biological mechanisms of parturition include the endocrine system, activation of cell signaling pathways that stimulate uterine muscle contraction, and activation of the inflammatory pathways, among others. Both preterm birth and postterm birth are linked to elevated neonatal morbidity and mortality. Preterm birth remains a major cause of perinatal mortality and morbidity. Reproductive assisted technologies contribute added morbidities. The risk of stillbirth plus early neonatal deaths doubles by 42 weeks of gestation (compared to the risk at term). Maternal risks of prolonged pregnancy include labor dystocia, cesarean delivery, and severe perineal injury. Many birth complications will negatively affect both the reproductive result and postnatal wellbeing, including the risk of adult diseases.

The present issue is devoted to the physiological and pathological mechanisms of parturition across the entire gestational period. The main focus will be on current findings and ideas that advance our understanding of the mechanisms underlying the physiological control of human birth and related conditions. We invite authors to present original research articles as well as review articles that will encourage future dialogue among clinicians and researchers. We welcome both clinical and basic findings.

Potential topics include but are not limited to:

  • The regulation of uterine relaxation and contraction
  • Endocrinology of parturition, genes, and environment
  • Management of labor
  • Preterm premature rupture of the membranes and fetal inflammatory response syndrome
  • Use of tocolytics, progestational agents, and corticoids
  • Postterm birth and fetal and maternal risks
  • Cervical ripening and induction of labor, misoprostol, prostaglandins, mifepristone, and other techniques
  • Intrapartum fetal assessment
  • Computerized FHR monitoring, ST-segment analyses, and fetal pulse oximetry
  • Third stage of labor
  • Maternal and perinatal mortality
  • Minimal care assistance in underdevelopment regions

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ogi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:

Obstetrics and Gynecology International
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Submission to final decision102 days
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