Cyclosporine A in Ullrich Congenital Muscular Dystrophy: Long-Term Results
Figure 4
Regenerating muscle fibers. Representative cross-section of the muscle biopsy of patient 6 after 3-month treatment with CsA. The section was stained with DAPI to identify nuclei (blue) and with antibodies against developmental myosin heavy chain (dMHC, green), as marker of regeneration, and desmin (red), as general marker of muscle cells. Several very small calibered muscle fibers dMHC-positive, which also display an intense and diffuse staining for desmin, are detected among myofibers, pointing to an active regeneration process. Bar, 20 μm.
