Macrophage Autophagy and Oxidative Stress: An Ultrastructural and Immunoelectron Microscopical Study
Ultrastructure of AAPH-treated macrophages. Nuclei appear intact with well-preserved nucleoli, a distinct nuclear envelope, and normal chromatin structure ((a) ×8000). Cells show the presence of many autophagic vacuoles of different sizes that enclose cytoplasmic components ((b) ×10000; (c) ×12500). N: nucleus; n: nucleolus; AV: autophagic vesicle; asterisks indicate mitochondria.