N-Acetylcysteine Supplementation Controls Total Antioxidant Capacity, Creatine Kinase, Lactate, and Tumor Necrotic Factor-Alpha against Oxidative Stress Induced by Graded Exercise in Sedentary Men
Table 3
Total antioxidant capacity (TAC), lactate (mmoL/L), creatine kinase (U/L), and tumor necrotic factor-alpha (TNF-α) (pg/mL) between the control and supplement groups at day 0 and 8.
Control (n = 13)
NAC (n = 16)
day 0
day 8
day 0
day 8
Pre-ex
Post-ex
Pre-ex
Post-ex
Pre-ex
Post-ex
Pre-ex
Post-ex
TAC
1.69 ± 0.07
1.49 ± 0.06#
1.73 ± 0.02
1.63 ± 0.03#
1.58 ± 0.06
1.38 ± 0.05#
1.71 ± 0.02
1.72 ± 0.03
(1.26–1.89)
(1.10–1.41)
(1.65–1.80)
(1.51–1.77)
(0.83–1.88)
(0.74–1.81)
(1.66–1.86)
(1.53–1.94)
Lactate
1.96 ± 0.35
3.67 ± 0.73#
2.01 ± 0.47
3.84 ± 0.61#
1.91 ± 0.32
3.72 ± 0.56#
2.05 ± 0.56
2.75 ± 0.55
(0.56–4.78)
(0.34–7.45)
(0.11–6.12)
(0.53–6.67)
(0.11–1.21)
(0.11–11.30)
(0.45–6.12)
(0.23–6.34)
CK
148.8 ± 14.0
164.7 ± 16.1#
147.7 ± 17.8
163.9 ± 20.1#
176.4 ± 12.7
190.5 ± 14.3#
137.7 ± 60.0
155.4 ± 18.1#
(89–282)
(90–290)
(87–310)
(95–372)
(123–285)
(111–301)
(56–248)
(95–290)
TNF-α
1.76 ± 0.22
5.71 ± 0.56#
1.40 ± 0.15
5.68 ± 0.52#
1.86 ± 0.19
6.93 ± 0.51#
1.38 ± 0.13
5.06 ± 0.47#
(0.78–3.12)
(4.81–8.45)#
(0.78–2.34)
(2.56–7.65)
(0.87–3.56)
(3.42–9.89)
(0.67–2.12)
(2.12–9.48)
Values are mean ± S.E (Min-Max). The values represent the range. #P < 0.05 compared to pre-exercise (pre-ex) period on the same day.
