Chopper Is Prodeath Regardless of the Effect of p75ICD on Sensitivity to Oxidative Stress
Figure 4
(a) Concentration-survival curve of HN33.11 cells to 6-hydroxydopamine (6-OHDA). Cell survival was determined by MTS assay as described in Methods. (b) Effects of Dox-induced expression of (A)-GFP on induction cell death by 6-OHDA in HN33.11 cells (clones A37 and A38). The stable lines indicated were plated at 5×105 cells per 60 mm dish and exposed to 6-OHDA (300 μM) for 1 hour and incubated for 48 hours prior to analysis by flow cytometric quantitation of sub-G1 nuclei. The results of one experiment of three performed are shown.
