Resveratrol Regulates Antioxidant Status, Inhibits Cytokine Expression and Restricts Apoptosis in Carbon Tetrachloride Induced Rat Hepatic Injury

Figure 9

Apoptotic assay was performed by using TUNEL assay (H.E. X 400); brown stained cells (indicated by arrows) are undergoing apoptosis. (a) Immunostaining of rat liver from normal control (group A) showed absent of brown staining, (b) CCl₄ control (group B) liver showing more staining indicative cells undergoing apoptosis; (c) resveratrol (100 mg/kg) + CCl₄ (group C) exhibited less cells undergoing apoptosis; (d) resveratrol (200 mg/kg) + CCl₄ (group D) exhibited very few number of brown-stained nuclei.

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