Resveratrol Regulates Antioxidant Status, Inhibits Cytokine Expression and Restricts Apoptosis in Carbon Tetrachloride Induced Rat Hepatic Injury

Table 4

Effect of the resveratrol treatment (100 mg/kg, 200 mg/kg body weight) for 8 weeks on the lipid peroxidation, glutathione reductase, and glutathione-s-transferase in liver tissue of CCl₄-induced rats.

Group	TBARS (nmol/g liver weight)	GSH content (nmol/mg protein)	GST content (nmole/min/mg protein)
A	106±2.4^∗∗	110±2.2^∗∗	1622±3.2^∗∗
B	303±3.2	75±1.5	720±2.5
C	210±3.5^∗	90±2.2^∗	1145±2.4^∗
D	129±2.7^∗∗#	107±1.2^∗∗#	1543±3.6^∗∗#

Group A, normal control; group B, CCl₄-administered rats; group C, resveratrol-(100 mg/kg) treated rats; group D, resveratrol-(200 mg/kg) treated rats.
Results are mean ± S.E.M for 10 animals; One way ANOVA followed by Dunnett’s multiple comparison test.
^∗𝑃<0.05 and ^∗∗𝑃<0.01 as compared with group B.
^#𝑃<0.05 as compared with group C.