Lipid-Lowering and Antioxidative Activities of Aqueous Extracts of Ocimum sanctum L. Leaves in Rats Fed with a High-Cholesterol Diet

Table 5

Effect of aqueous extracts of Ocimum sanctum L. leaves on serum lipid peroxide, hepatic and cardiac tissue lipid peroxide and antioxidant enzymes activity in HC rats.

	Group
	Normal	HC	HC + OS
Serum TBAR (μmole/L)	1.8±0.08^a	2.7±0.04^b	2.1±0.1^c
Liver
TBARS (nmoleMDA/mg protein)	0.88±0.06^a	1.38±0.04^b	0.59±0.05^c
GPx (μmole/min/mg protein)	1.3±0.06^a	0.97±0.02^b	1.19±0.03^a
CAT (μmole/min/mg protein)	360±16.6^a	275±18^b	340±28^a
SOD (unit/mg protein)	103±13.9^a	40.1±3.29^b	54.4±2.32^b
Heart
TBARS (nmoleMDA/mg protein)	1.0±0.05^a	1.83±0.05^b	0.61±0.07^c
GPx (μmole/mg protein)	0.28±0.02^a	0.20±0.02^b	0.30±0.02^a
CAT (μmole/min/mg protein)	6.95±0.38^a	5.82±0.31^b	7.33±0.47^a
SOD (unit/mg protein)	25.3±2.1^a	14.3±1.2^a	82.8±11.7^c

Values are shown as means ± SEM of seven rats per group.
Values with different superscripts in the same row are significantly different at 𝑃<0.05.
TBARS: thiobarbituric acid reactive substances; GPx: glutathione peroxidase; CAT: catalase; SOD: superoxide dismutase.