Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats

Figure 3

Curcumin (60 mg/kg/day) ameliorated 5/6NX-induced glomerular sclerosis at the end of the study (day 30). Upper panels shows representative images of the groups studied. 10X. Lower panel show quantitative data in 5/6NX and 5/6NX+CUR groups. Glomerular sclerosis was absent in control and CUR groups. Data are mean ± SEM of 8–10 rats. *𝑃<0.05 versus 5/6NX.

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