Silica Nanoparticles Sensitize Human Multiple Myeloma Cells to Snake (Walterinnesia aegyptia) Venom-Induced Apoptosis and Growth Arrest
Figure 4
Time- and dose-dependent effect of WEV and WEV+NP treatment on cell viability. Cell viability was assessed using the MTT assay. MM cells from patients with MM (a) and XG2 cells (b) were treated overnight with different concentrations (0, 1, 5, 10, 25, 50, 100, and 1000 ng/mL) of NP (open circles), WEV (gray triangles), or WEV+NP (closed black squares). MM cells from patients with MM (c) and XG2 cells (d) were treated with 25 ng/mL of NP (open circles), 25 ng/mL of WEV (gray triangles), or 10 ng/mL of WEV+NP (closed black squares) for different incubation times (0, 1, 2, 6, 12, 24, 36, and 48 hrs). The data collected from independent experiments () are shown, and the results are expressed as the mean percentage of viable cells SEM.
