Research Article

Coffee Polyphenols Change the Expression of STAT5B and ATF-2 Modifying Cyclin D1 Levels in Cancer Cells

Table 4

List of overexpressed genes in HT29 cells upon incubation with caffeic acid.

Gene symbolGene title valueFC absoluteRegulation

SULT1B1Sulfotransferase family, cytosolic, 1B, member 10.021.3Up
BCL6BB-cell CLL/lymphoma 6, member B (zinc finger protein)3.00E-041.3Up
KCNJ5Potassium inwardly-rectifying channel, subfamily J, member 50.011.31Up
EPORErythropoietin receptor0.021.32Up
DNAJC21DnaJ (Hsp40) homolog, subfamily C, member 210.0491.33Up
STAT5BSignal transducer and activator of transcription 5B0.0121.33Up
FSTFollistatin0.0211.37Up
CD84CD84 molecule0.0331.37Up
THRAThyroid hormone receptor, alpha0.0171.37Up
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 30.0281.4Up
SIAESialic acid acetylesterase0.012.42Up
HINT3Histidine triad nucleotide-binding protein 30.0332.6Up

The table shows the list of overexpressed genes by 1.3-fold with a value obtained in cells treated with caffeic acid and includes the gene symbol for all genes, their associated description. The ratio columns correspond to the absolute fold change in expression relative to the control group and the type of regulation (up: upregulation).