Riluzole-Triggered GSH Synthesis via Activation of Glutamate Transporters to Antagonize Methylmercury-Induced Oxidative Stress in Rat Cerebral Cortex

Table 2

Effects of MeHg exposure and riluzole pretreatment on GSH, Glu, and Gln levels.

Groups	GSH (μmol·g^−1pro)	Glu (μmol·g^−1 pro)	Gln (mmol·g^−1 pro)
Control	32.77±4.01	56.76±10.23	0.26±0.02
Riluzole	39.16±7.46^*	45.41±6.90^*	0.36±0.05^**
MeHg	21.86±2.70^**	71.49±11.98^**	0.17±0.02^**
Riluzole + MeHg	28.34±3.43^#	54.19±3.08^##	0.25±0.04^##

Data are mean ± SD, 𝑛=6 each.
^∗𝑃<0.05, ^**𝑃<0.01 denote statistical significance compared with control group;
^#𝑃<0.05, ^##𝑃<0.01 denote statistical significance compared with MeHg alone group.