The Redox Imbalance and the Reduction of Contractile Protein Content in Rat Hearts Administered with L-Thyroxine and Doxorubicin

Table 2

Concentration of NADPH (nmol/g tissue), MDA (nmol/g tissue), and the number of abasic sites in genomic DNA (AP/100 kbp) in the cardiac muscle.

	NADPH	MDA	AP in gDNA
Control	19.95±5.2	2.37±0.39	7.34±2.84
DOX	24.53±6.79	2.30±0.66	6.56±1.99
2T4+ DOX	16.12±5.30	3.75±0.66^a,b	9.65±3.79
0.2T4+ DOX	9.27±1.72^a,b	3.13±0.65^a,b	6.84±3.29
2T4	22.13±5.25	3.84±1.45^a	8.46±5.48
0.2T4	18.10±5.73	3.03±0.94	6.29±1.51

Data presented as mean ± SD; ^a𝑃<0.05 versus control; ^b𝑃<0.05 versus DOX.