The Redox Imbalance and the Reduction of Contractile Protein Content in Rat Hearts Administered with L-Thyroxine and Doxorubicin

Table 4

Histological features of the cardiac muscle in experimental and control groups.

	Interstitial		Perivascular fibrosis	Cardiomyocytes		Inflammation
	Fibrosis	Edema		Vacuolisation	Irregular cytoplasm staining
Control	2	—	1	—	—	1
DOX	2	—		2	1	3
2T4+ DOX	4	—	1	—	3	5
0.2T4+ DOX	4	—	—	3	2	3
2T4	3	3	—	—	1	1
0.2T4	2	8	—	—	—	3

Samples from all rats in all experimental and control groups were evaluated (𝑛=8/group). A single animal may be represented more than once in the listing of individual histological changes.