Blockade of TGF- 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats
Figure 2
Effect of P144 on cardiac Nox2 subunit expression. (a) mRNA levels of Nox2 expressed as a ratio of gene to 18S values from rat heart. (b) Expression of the Nox2 protein levels relative to α-tubulin in the rat heart. Representative western blot of the four groups of rats are shown at the upper part. Histograms represent mean ± SEM (). V-WKY means vehicle-treated normotensive rat; P144-WKY, P144-treated WKY rat; V-SHR, vehicle-treated spontaneously hypertensive rat; P144-SHR, P144-treated SHR. * versus the other groups.
