Research Article

Blockade of TGF- 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats

Figure 7

Effect of P144 on TGF-β-1-induced NADPH oxidase activity in Rat-2 fibroblasts. Cells were incubated with 10 ng/mL TGF-β 1 (TGF-β 1), 200 μg/mL P144 (P144), and TGF-β 1 and P144 (TGF-β 1+P144). Data are expressed as fold increase versus control cells incubated in the absence of TGF-β 1 and P144 (Control). Histogram represents mean ± SEM ( ). *   versus the other groups.
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