Research Article

Preventive Effects of Epigallocatechin-3-O-Gallate against Replicative Senescence Associated with p53 Acetylation in Human Dermal Fibroblasts

Table 1

IC50 values of EGCG to proliferating and senescent primary cells.

Primary cellsIC50 of EGCG, μM (μg/mL)

Proliferating RVSMCs1100 (500)
Senescent RVSMCs1155 (529)
Proliferating HACs320 (147)
Senescent HACs327 (150)
Proliferating HDFs620 (284)
Senescent HDFs631 (289)