Research Article
Preventive Effects of Epigallocatechin-3-O-Gallate against Replicative Senescence Associated with p53 Acetylation in Human Dermal Fibroblasts
Table 1
IC50 values of EGCG to proliferating and senescent primary cells.
| Primary cells | IC50 of EGCG, μM (μg/mL) |
| Proliferating RVSMCs | 1100 (≈500) | Senescent RVSMCs | 1155 (≈529) | Proliferating HACs | 320 (≈147) | Senescent HACs | 327 (≈150) | Proliferating HDFs | 620 (≈284) | Senescent HDFs | 631 (≈289) |
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