Thymoquinone, the Nigella sativa Bioactive Compound, Prevents Circulatory Oxidative Stress Caused by 1,2-Dimethylhydrazine in Erythrocyte during Colon Postinitiation Carcinogenesis

Table 2

Malondialdehyde (MDA) and conjugated dienes (CD) levels in erythrocytes of adult rat controls or treated with DMH, TQ, and different (TQ + DMH) treatments.

	Control	TQ	DMH	Pretreatment	Posttreatment
CD^a	1.27 ± 0.09	1.4 ± 0.25	1.29 ± 0.13	1.24 ± 0.04	1.78±0.194^∗∗∗+++
MDA^b	13.11 ± 0.75	14.74 ± 1.81	20.59±0.54^∗∗∗	17.39±1.025^∗∗∗++	20.11±1.225^∗∗∗

Values are means ± SE for five rats in each group.
DMH, TQ, and different (TQ + DMH) groups versus control group: ^∗𝑃<0.05; ^∗∗𝑃<0.01; ^∗∗∗𝑃<0.001, TQ + DMH groups versus DMH: ⁺𝑃<0.05,⁺⁺𝑃<0.01,⁺⁺⁺𝑃<0.001.
^aμmol/mg of protein.
^bμmol hydroperoxides/mg of protein.