Table 3: Pharmacokinetic parameters for oral and i.v. administration of SAC in the serum of rats.A

ParameterOral administrationi.v. administration

Distribution volume ( )1.2 L1.3 L
Elimination half-life ( )2.7 h2.6 h
Total clearance0.3 L/h0.3 L/h
Peak concentration ( )100.1 mg/L at 30 min
AUC0–t value293.5 mg·h/L322.6 mg·h/L

ASynthesized from [19]. AUC0–t : area under the plasma concentration versus time curve from time zero to the last quantifiable concentration.