Adenine Nucleotide Translocase, Mitochondrial Stress, and Degenerative Cell Death

Figure 1

Projected localization of A90, L98, A114, A123, and the arginine triplet on the crystal structure of bovine Ant1 in the cytosolic conformation bound by CATR (yellow) [25]. The corresponding amino acids in yeast Aac2 are also indicated. R252, R253, and R254 in yeast correspond to R234, R235, and R236 in the bovine protein. IMS, intermembrane space; M, matrix.