NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice

Figure 9

Effects of 6-OHDA on GFAP expression in the striatum. (a) the graph depicts the mean optical density data of 5 to 6 samples in each case. ***𝑃<0.001 (Wt saline versus Wt 6-OHDA) and ***𝑃<0.001 (Wt apocynin saline versus Wt apocynin 6-OHDA). (b) representative digital images of GFAP-like immunoreactivity in the saline-injected Wt, 6-OHDA-injected Wt, saline-injected gp91^phox, 6-OHDA-injected gp91^phox−/−, apocynin-treated Wt injected with saline, and apocynin-treated Wt injected with 6-OHDA mice.

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