Research Article

Neuroprotective Effect of Ginkgolide B on Bupivacaine-Induced Apoptosis in SH-SY5Y Cells

Figure 1

Proliferation effects of bupivacaine on SH-SY5Y cells and GB weakened bupivacaine-induced cell injury in SH-SY5Y cells. (a) Cells were incubated in the presence or absence of various concentrations of bupivacaine for 24 h ( versus control group). Cell growth was determined by the MTT assay. (b) Cell viability was decreased by treatment with 1 mmol/L bupivacaine for 24 hours. Decreased viability was inhibited by GB pretreatment for 6 hours, except for cells treated with 5 μmol/L GB ( versus nonpretreated group). Each data point represents the mean ± SD of 6 separate experiments.
159864.fig.001a
(a)
159864.fig.001b
(b)