The Risk of Heart Failure and Cardiometabolic Complications in Obesity May Be Masked by an Apparent Healthy Status of Normal Blood Glucose
Figure 7
Effect of hemin on histological lesions in the left ventricle of ZLs and ZFs. (a) Representative Mason’s trichrome-stained images revealing severe cardiac muscle scaring and collagen deposition in ZFs. (b) Semiquantitative evaluation showed that hemin therapy reduced collagen deposition in ZFs. (c) Representative hematoxylin and eosin-stained images revealing severe longitudinal muscle-fiber thickness in ZFs. (d) Quantitative evaluation showed that hemin reduced longitudinal muscle-fiber thickness. ± SEM; rats per group (*, ** versus all groups).