The Risk of Heart Failure and Cardiometabolic Complications in Obesity May Be Masked by an Apparent Healthy Status of Normal Blood Glucose

Table 1

Effect of hemin and stannous mesoporphyrin (SnMP) on physiological and biochemical variables in Zucker fatty (ZF) and Zucker lean (ZL) rats.

Parameters	Animal groups
	ZL control	ZL + hemin	ZF control	ZF + hemin	ZF + hemin + SnMP	ZF + vehicle
Body weight (g)	472.9±9.7	445.5±11.6^†	746.8±21.5^§	685.9±14.7^§	691.4±15.2^$	702.8±24.6
Fasting glucose; (mmo/L)	7.2±0.6	6.5±0.3^∗	8.2±0.5^§	6.9±0.4^∗	8.5±0.4^∗	8.1±0.4
Heart weight (g)	1.5±0.03	1.1±0.02^†	3.4±0.06^§	2.0±0.04^§	3.0±0.03^$	3.1±0.04
Cardiac hypertrophy; (g/Kg body weight)	3.1±0.07	2.5±0.06^∗	4.6±0.16^§	2.9±0.08^∗	4.4±0.17^∗	4.4±0.09

^†𝑃<0.05 versus ZL; ^$𝑃<0.05 versus ZF; ^§𝑃<0.05 versus ZL control; ^∗𝑃<0.05 versus ZF-control or ZL-control.