Exacerbated Airway Toxicity of Environmental Oxidant Ozone in Mice Deficient in Nrf2
Figure 2
Lung injury after acute exposure. Lactate dehydrogenase levels (a), total cells (b), neutrophils (c), lymphocytes (d), epithelial cells (e), and total protein concentrations (f) in fluid recovered by bronchoalveolar lavage (BAL) from and mice 3, 6, or 24 hr after 3 hr exposure to 2 ppm . Control mice were exposed to filtered air. All data are presented as mean ± SEM. *Significantly different from genotype-matched air controls (). +Significantly different from exposure-matched mice (). –8 per group.
