Attenuation of -Amyloid-Induced Oxidative Cell Death by Sulforaphane via Activation of NF-E2-Related Factor 2
Figure 1
Protective effect of sulforaphane (SUL) on A-induced cytotoxicity and apoptotic cell death. SH-SY5Y cells were incubated with 15 M A with or without SUL (1 M, 2 M, and 5 M) for 24 h. (a) Viable cells were determined by MTT dye reduction assay. Cell viability is expressed as the percentage of control. Data are represented as mean ± S.D. . , control versus A and , A versus A + SUL. (b) DNA fragmentation was measured by TUNEL. (A) Vehicle-treated control; (B) A alone (15 M); (C) A (15 M) + SUL (5 M); (D) quantification of apoptotic cell death (%).
