Research Article

Ameliorating Effect of Various Fractions of Rumex hastatus Roots against Hepato- and Testicular Toxicity Caused by CCl4

Table 5

Effects of various fractions of R. hastatus roots on phase II antioxidant enzymes and DNA fragmentation.

GroupGST
(nM/mg protein)
GPx
(nM/mg protein)
GR
(nM/mg protein)
GSH
(µM/g tissue)
QR
(nM/mg protein)
Percent DNA injuries

Control150.21 ± 4.11g110.71 ± 3.23e198.47 ± 4.72h17.69 ± 1.11e105.33 ± 1.34g9.21 ± 1.30e
Oil + DMSO146.34 ± 4.10g104.56 ± 3.10e190.69 ± 4.39h15.40 ± 1.30e107.12 ± 1.46g8.38 ± 1.63e
CCl487.48 ± 3.45a57.86 ± 2.67a120.76 ± 3.02a7.63 ± 0.75a63.34 ± 1.01a51.11 ± 2.02a
Sily + CCl4122.22 ± 3.18e94.62 ± 2.47d158.61 ± 2.35g13.73 ± 0.73d91.54 ± 2.11f22.43 ± 1.57d
HRR + CCl494.05 ± 2.56b68.44 ± 2.37b127.11 ± 2.34b10.08 ± 0.39b69.69 ± 1.72b42.22 ± 1.27b
ERR + CCl495.67 ± 2.48b70.37 ± 2.42b127.51 ± 2.55b10.25 ± 0.36b71.47 ± 1.95b35.33 ± 2.15c
CRR + CCl4100.28 ± 2.27c76.22 ± 2.71c132.17 ± 2.33c11.17 ± 0.28c75.56 ± 1.38c26.44 ± 1.73d
BRR + CCl4119.16 ± 3.15e80.51 ± 2.33c144.43 ± 2.26e12.19 ± 0.43d83.24 ± 2.82e25.53 ± 2.15d
MRR + CCl4130.53 ± 2.34f88.61 ± 2.20c150.39 ± 2.41f12.36 ± 0.15d90.97 ± 2.61f23.78 ± 1.23d
ARR + CCl4108.26 ± 3.68d85.47 ± 2.62c139.40 ± 2.16d11.53 ± 0.32c79.87 ± 2.28d25.73 ± 1.56d
HRR alone149.67 ± 3.63g107.34 ± 3.57e192.22 ± 2.23h16.22 ± 0.50e108.34 ± 1.41g7.66 ± 1.27e
ERR alone155.87 ± 4.58g106.48 ± 4.53e201.47 ± 3.50h18.37 ± 0.38e100.44 ± 1.70g7.22 ± 1.43e
CRR alone148.51 ± 3.45g109.38 ± 3.22e191.71 ± 3.00h15.30 ± 0.38e109.34 ± 1.24g7.80 ± 1.28e
BRR alone156.63 ± 4.43g107.68 ± 4.34e195.45 ± 3.45h17.04 ± 0.38e108.45 ± 1.89g8.34 ± 0.28e
MRR alone156.52 ± 3.23g111.51 ± 3.38e200.10 ± 2.69h18.10 ± 0.23e110.71 ± 1.57g8.23 ± 0.93e
ARR alone157.77 ± 3.76g102.57 ± 3.43e197.53 ± 4.02h15.37 ± 0.20e109.34 ± 1.45g6.78 ± 1.73e

Values are mean ± SD (06 number). Sily: Silymarin.
(means with different letters) indicate significance at .