Acute Hyperglycemia Abolishes Ischemic Preconditioning by Inhibiting Akt Phosphorylation: Normalizing Blood Glucose before Ischemia Restores Ischemic Preconditioning

<table>Myocardial infarct size after 40 minutes of LAD occlusion and 60 minutes of reperfusion. Acute hyperglycemia exacerbates infarct size. Normalization of blood glucose levels before LAD occlusion failed to counteract the hyperglycemic effect.</table>

Oxidative Medicine and Cellular Longevity

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Figure 2: Acute Hyperglycemia Abolishes Ischemic Preconditioning by Inhibiting Akt Phosphorylation: Normalizing Blood Glucose before Ischemia Restores Ischemic Preconditioning 

Figure 2 | Acute Hyperglycemia Abolishes Ischemic Preconditioning by Inhibiting Akt Phosphorylation: Normalizing Blood Glucose before Ischemia Restores Ischemic Preconditioning 