Oxidative Medicine and Cellular Longevity / 2013 / Article / Tab 2

Clinical Study

Protein Sulfhydryl Group Oxidation and Mixed-Disulfide Modifications in Stable and Unstable Human Carotid Plaques

Table 2

Levels of protein-bound and total LMW-thiols from stable and unstable plaque extracts.

Stable (nmol/g prot)Unstable (nmol/g prot)P value

Protein-bound LMW-thiols
 Cys-Gly13.2 (11.3–16.9)12.1 (8.4–17.1)0.339
 Hcy5.7 ± 3.26.7 ± 4.00.468
 Cys146.0 (117.5–211.4)219.6 (147.6–301.9)0.089
 GSH41.1 (23.2–77.9)80.8 (42.0–122.1)0.168
 Glu-Cys14.1 ± 5.615.3 ± 7.00.593

Total283 ± 126373 ± 1110.034

Total LMW-thiols
 Cys-Gly53.8 ± 21.144.6 ± 19.70.205
 Hcy15.0 ± 10.220.7 ± 12.30.179
 Cys600 ± 276576 ± 2080.767
 GSH128.6 (95.1–202.4)171.2 (97.2–346.4)0.189
 Glu-Cys69.2 ± 29.462.7 ± 29.80.534

Total900 ± 273960 ± 2930.555

Values are either mean ± SD or median with ranges (in parenthesis).
LMW-thiols levels were expressed as nmol/g of extracted proteins.
Total LMW-thiols are the sum of free LMW-thiols and protein-bound LMW-thiols.

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