The Influence of Long Term Hydrochlorothiazide Administration on the Relationship between Renin-Angiotensin-Aldosterone System Activity and Plasma Glucose in Patients with Hypertension

Table 2

Comparison of GLU concentrations and changes between paired RAAS activity groups after one year of medication (mean ± sd).

RAAS activity; after 1 year of medication	Groups	GLU baseline; (mmol·L^−1)	ΔGLU* (mmol·L^−1)
PRA	Elevated	5.71±3.05	−0.26±0.26
	Nonelevated	5.12±2.44	−1.36±0.23
	t	−0.981	−3.502
	P	0.329	0.003
ACE	Elevated	5.24±2.39	−0.76±0.23
	Nonelevated	5.29±2.63	−1.09±0.19
	t	0.116	−1.083
	P	0.908	0.281
Ang II	Elevated	5.58±2.91	−0.17±0.18
	Nonelevated	5.23±2.59	−1.07±0.21
	t	−0.576	−2.865
	P	0.566	0.005
ALD	Elevated	5.41±2.80	−0.67±0.28
	Nonelevated	5.18±2.44	−1.12±0.19
	t	−0.441	−1.338
	P	0.66	0.184

^∗Δ refers to mean changes when compared with baseline level after one year of hydrochlorothiazide.