Rosmarinic Acid-Rich Extracts of Summer Savory (Satureja hortensis L.) Protect Jurkat T Cells against Oxidative Stress

Table 1

Effects of S. hortensis extracts and of the partially purified rosmarinic-acid fraction on the generation of superoxide (O₂⁻) and peroxyl (LOO^•) radicals in Jurkat cells subjected to hydrogen peroxide-induced oxidative stress.

	Hydrogen peroxide concentration, 𝜇M
	0		25		50
	EPR signal intensity, arbitrary units
	O2^−	LOO^•	O2^−	LOO^•	O2^−	LOO^•
No additives (control)	0	0	2.4±0.2	3.0±0.2	3.1±0.1	3.8±0.3
Chloroform extract	0	0	2.0±0.2	3.2±0.2	2.1±0.2^∗	2.8±0.3^∗
Ethyl acetate extract	0	0	2.0±0.2	3.2±0.2	2.1±0.2^∗	2.8±0.3^∗
Ethanolic extract	0	0	0^∗	0^∗	0.1±0.1^∗	0^∗
Aqueous extract	0	0	0^∗	0.3±0.1^∗	0.1±0.1^∗	0.5±0.1^∗
Rosmarinic acid fraction	0	0	1.0±0.2^∗	2.2±0.2^∗	1.1±0.2^∗	1.8±0.3^∗

Values represent averages of five replications ± standard deviations. Values marked with the asterisk are significantly different from the control in the same column at 𝑃≤0.05, according to Student’s 𝑡-test.