Rosmarinic Acid-Rich Extracts of Summer Savory (Satureja hortensis L.) Protect Jurkat T Cells against Oxidative Stress

Table 6

Effects of the ethanolic S. hortensis extract and of the partially purified rosmarinic-acid fraction on the production of interleukins by Jurkat cells in the presence of hydrogen peroxide.

	IL-2, pg mL^−1	IL-10, pg mL^−1	IL-2/IL-10
No additives (control)	0.90±0.05	3.21±0.04	0.28±0.04
H2O2 25 μM	2.61±0.04^∗	6.80±0.05^∗	0.38±0.01
H2O2 25 μM + S. hortensis (ethanolic extract)	15.30±0.04^∗	20.01±0.08^∗	0.76±0.07
H2O2 25 μM + S. hortensis rosmarinic acid fraction	20.80±0.07^∗	38.40±0.06^∗	0.54±0.07

Values represent averages of five replications ± standard deviations. Values marked with the asterisk are significantly different from the control in the same column at 𝑃≤0.05, according to Student’s 𝑡-test.