Protective Effects of Extracts from Fructus rhodomyrti against Oxidative DNA Damage In Vitro and In Vivo

Table 8

The levels of 8-OHdG in plasma and tissues.

Treatment groups	Plasma (ng/mL)	Kidney (ng/mL)	Liver (ng/mL)
Saline (control)	0.69±0.08	1.12±0.15	0.92±0.12
KBrO3 (125 mg/kg body weight)	9.65±1.26^△△	21.65±2.94^△△	13.73±2.13^△△
FR (150 mg/kg body weight) + KBrO3	5.27±0.68^∗∗	12.45±1.57^∗	7.82±1.28^∗∗
FR (300 mg/kg body weight) + KBrO3	2.59±0.23^∗∗	3.38±0.45^∗∗	2.73±0.37^∗∗
FR (300 mg/kg body weight) alone	0.75±0.10	1.05±0.18	0.89±0.15

Values were expressed as mean ± SD, 𝑛=6. The dose of KBrO₃ was 125 mg/kg body weight in each group.
^△𝑃<0.05 and ^△△𝑃<0.01 compared with the control group.
^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared with KBrO₃-treated rats.