Oxidative Stress and Mitogen-Activated Protein Kinase Pathways Involved in Cadmium-Induced BRL 3A Cell Apoptosis
Effect of Cd and NAC on ROS generation of BRL 3A cells. Cultured cells were exposed to 0 μmol/L to 40 μmol/L Cd and pre-treated with or without 2 mmol/L NAC for 12 h. Data are presented as mean ± SD of three independent experiments performed in triplicate. Significant difference: *, **, compared with the control. #, ##, compared with the 20 μmol/L Cd group.