Oxidative Medicine and Cellular Longevity / 2013 / Article / Fig 1

Review Article

Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac Sirtuins

Figure 1

The electron transport chain (ETC) responsible for ATP and ROS production in mitochondria. ROS: reactive oxygen species, TCA: tricarboxylic acid, NADH & NAD+: nicotinamide adenine dinucleotide reduced form & oxidized form, FADH2 & FAD; flavin adenine dinucleotide reduced form and oxidized form, ADP: adenosine diphosphate, ATP: adenosine triphosphate, Co Q: coenzyme Q, Cyt c: cytochrome c, UCP: uncoupling protein.