Oxidative Medicine and Cellular Longevity / 2013 / Article / Fig 2

Review Article

Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac Sirtuins

Figure 2

Possible mechanisms by which CR attenuates oxidative stress. CR: caloric restriction, PGC-1α: peroxisome proliferator-activated receptor γ coactivator 1α, NRF1: nuclear respiratory factor 1, FoxO1: forkhead transcriptional factor 1, NOS: nitric oxide synthase.