Mild Systemic Oxidative Stress in the Subclinical Stage of Alzheimer’s Disease

Table 4

Monocyte activation parameters. INT (cognitively intact patients; 𝑛=42) and AD (patients with probable Alzheimer’s disease; 𝑛=23); GMFI: geometric mean fluorescence intensity; % URQ: percentage of events in the upper right quadrant. Values shown correspond to the means ± SEM. Comparison between average results of the groups was performed using Student 𝑡 test for independent samples.

Parameter	INT	AD
HLADR (GMFI)	109.93±10.59	177.74±30.64^∗
CD11B (GMFI)	406.74±39.24	412.92±48.97
IL-1α (%URQ)	65.78±2.46	82.82±6.52^∗
IL-6 (%URQ)	52.89±4.31	49.71±6.57
TNF-α (%URQ)	6.85±1.28	8.26±2.47
Oxidative metabolism (GMFI)	266.32±38.99	257.77±63.07

 *𝑃<0.05 was considered significant.