Oxidant Status and Lipid Composition of Erythrocyte Membranes in Patients with Type 2 Diabetes, Chronic Liver Damage, and a Combination of Both Pathologies

Table 3

Relations of phospholipids and cholesterol in RBC membranes obtained from control subjects and in patients with type 2 DM and cirrhosis.

Parameter	Healthy (𝑛=60)	Diabetes (𝑛=60)	Cirrhosis (𝑛=70)	Diab + Cirrhos (𝑛=25)
Total phospholipids (nmoles/mg)	171±44	168±42	185±44	453±87^∗,∗∗∗
PC/PE ratio	2.72±0.62	2.34±0.54^∗	2.71±0.58	2.76±0.46^∗∗
Cholesterol/T. phospholipids	0.10±0.02	0.11±0.03	0.13±0.03^∗	0.09±0.02^∗∗∗

Results are expressed as mean ± SD of determinations done in RBC membranes from controls (𝑛=60), patients with type 2 DM (𝑛=60), cirrhotic patients (𝑛=70), and diabetic patients with cirrhosis (𝑛=25). PC: phosphatidylcholine; PE: phosphatidylethanolamine; T: total; Diab + Cirrhos: diabetes + cirrhosis. Statistical significance: *𝑃<0.01, versus control; **𝑃<0.01, versus DM or versus cirrhosis; ***𝑃<0.01, versus both the diabetes and cirrhosis groups, separately.