Lack of HXK2 Induces Localization of Active Ras in Mitochondria and Triggers Apoptosis in the Yeast Saccharomyces cerevisiae
Figure 5
Mitochondrial membrane potential and morphology in W303-1A and hxk2Δ strains upon acetic acid treatment. W303-1A and hxk2Δ exponentially growing cells were treated with different concentrations (40–80–120 mM) of acetic acid for 200 minutes at 30°C. DiOC6 uptake was assessed using both flow cytometry (a) and fluorescence microscopy (b). Photomicrographs illustrate the alteration of the tubular mitochondrial network to clustered mitochondrial morphology, particularly exacerbated in hxk2Δ cells after acetic acid treatment.
