Neuroprotective Effects of a Variety of Pomegranate Juice Extracts against MPTP-Induced Cytotoxicity and Oxidative Stress in Human Primary Neurons
Figure 1
Effect of PJE on MPTP-induced NAD+ and ATP depletions and cell viability in human neurons. Effect of (a) Helow, Malasi, Qusum, and Hamadh varieties on NAD+ depletion in the presence of MPTP (0.05 mM) for 24 hours (* compared with 0.05 mM MPTP alone); (b) Helow, Malasi, Qusum, and Hamadh varieties on extracellular LDH activity in the presence of MPTP (0.05 mM) (* compared with 0.05 mM MPTP alone), for each treatment group; (c) Helow, Malasi, Qusum, and Hamadh varieties on intracellular ATP levels in the presence of MPTP (0.05 mM) (* compared with 0.05 mM MPTP alone), for each treatment group; (d) Helow, Malasi, Qusum, and Hamadh varieties alone on extracellular LDH activity (* compared with control), for each treatment group; (e) Helow, Malasi, Qusum, and Hamadh varieties alone on intracellular NAD+ levels (* compared with control), for each treatment group.
