Research Article

Neuroprotective Effects of a Variety of Pomegranate Juice Extracts against MPTP-Induced Cytotoxicity and Oxidative Stress in Human Primary Neurons

Figure 2

Effect of PJE on MPTP-induced increase in lipid peroxidation and MPTP-mediated changes to endogenous antioxidant activities in human neurons. Effect of (a) Helow, Malasi, Qusum, and Hamadh varieties on MDA levels in the presence of MPTP (0.05 mM) for 24 hours (* compared with 0.05 mM MPTP alone); (b) Helow, Malasi, Qusum, and Hamadh varieties on GPx activity in the presence of MPTP (0.05 mM) for 24 hours (* compared with 0.05 mM MPTP alone); (c) Helow, Malasi, Qusum, and Hamadh varieties on intracellular GSH levels in the presence of MPTP (0.05 mM) for 24 hours (* compared with 0.05 mM MPTP alone); (d) Helow, Malasi, Qusum, and Hamadh varieties on SOD activity in the presence of MPTP (0.05 mM) for 24 hours (* compared with 0.05 mM MPTP alone); (e) Helow, Malasi, Qusum, and Hamadh varieties on CAT activity in the presence of MPTP (0.05 mM) for 24 hours (* compared with 0.05 mM MPTP alone).
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