Research Article
Examining the Impact of Skin Lighteners In Vitro
Table 2
Summary of gene expression indicated by ratio of medians for three skin lightening agents, hydroquinone (0.0001%), kojic acid (0.01%), and niacinamide (0.01%) looking at cytochrome c oxidase-1 (COX1) and ferritin (FTH1) expression on normal human epidermal keratinocytes. Ratios of medians higher than 1.3 typically indicate a statistically significant upregulation of the gene. Values less than 0.7 typically demonstrate a statistically significant downregulation of the gene.
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